Coleus Forskohlii root extract
Coleus forskohli is a perennial that can be found in India, Burma and Thailand. Since ancient times the root of this plant has been used in the treatment of heart and lung diseases, intestinal spasms, insomnia, and convulsions.
An active ingredient of coleus forskohli is forskolin. It is famous for its ability to increase the amount of cyclic adenosine monophosphate (cAMP) in cells by activating an enzyme which is called adenylate cyclase. Actually cAMP is one of the most important cell regulating compounds. Usually cAMP is formed by adenylate cyclase activation due to hormonal stimulation at the cell receptor site. Forskolin seems to bypass this reaction and allows for an increase in intracellular cAMP to occur. Moreover, forskolin can also stimulate digestive enzymes. And it can help to digest and assimilate food better. It has been shown to increase nutrient absorption in the small intestine.
Coleus forskohlii root extract is well known among those whose aim is to lose weight. It is famous for its ability to breakdown stored fat as well as inhibit the synthesis of adipose tissue. In addition it increases thyroid hormone production and release thereby increasing metabolism. The lipolysis is actually regulated by cAMP. Forskolin has been shown to not only enhance the breakdown of fat, but it may also prevent fat storage.
Some studies claim that forskolin may also assist in dilating blood vessels and improving the forcefulness with which the heart pumps blood. It may help to reduce blood pressure and improved heart function in people with cardiomyopathy.
Coleus is also useful for people with asthma, intestinal colic, uterine cramps.
This herb is considered to be useful in reducing the risk of glaucoma as the ophthalmic preparation of forskolin to the eyes lowers eye pressure.
In addition, this herb is found to be effective in such skin conditions as eczema and psoriasis.
Studies showed that forskolin is safe and effective and has a great amount of potential as a sports supplement. However if we talk about dietary supplements, more human research should be done.
You can purchase coleus in the form of root extract. Some medical professionals have recommended taking 50-100 mg of standardized coleus extract 2-3 times per day. However these amounts have not been confirmed by clinical research yet. That is why you’d better consult your practitioner before buying and using coleus.